This map from Hog Island Press in Philadelphia organizes 42 Great American Novels by the locations in which they are set.
Want to read a book set in New Orleans? This map lists three.
California, Florida, and Chicago all have their share of classic American novels, as does the Northeast. The Dakotas, though, are a barren wasteland when it comes to great literature. Miles and miles of untapped literary potential there. Go figure.
See the map for yourself (or buy a copy for your favorite book blogger) at the Hog Island Press website.